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How Multiple Sclerosis is Diagnosed

Posted by:

Johannes Sauer

Updated at: June 23, 2025

Table of Contents
  1. How Multiple Sclerosis is Diagnosed

  2. The First Signs: You’re Not Imagining Things

  3. What Is Multiple Sclerosis?

    1. Medical History & Neurological Exam

    2. MRI Imaging

    3. Lumbar Puncture (Spinal Tap)

    4. Evoked Potential Tests

    5. Blood Tests

  4. What Happens After a Diagnosis?

  5. Supportive Footwear Can Help

How Multiple Sclerosis is Diagnosed

Multiple Sclerosis is diagnosed through a combination of neurological exams, MRI scans, lumbar punctures (spinal taps), and evoked potential tests. Doctors use these tools to detect damage in the brain and spinal cord, rule out other conditions, and confirm patterns consistent with MS. Because symptoms vary from person to person, an MS diagnosis often requires multiple steps over time.

The First Signs: You’re Not Imagining Things

Experiencing unexplained fatigue, tingling, blurred vision, or trouble walking? You’re not imagining things—and you’re definitely not alone. For many people, the path to understanding what’s going on in their body starts with a series of small signs that don’t make sense—until they do. Whether you’re personally feeling the weight of these changes or supporting someone who is, it can be overwhelming to live in limbo without a clear diagnosis.

Understanding how Multiple Sclerosis is diagnosed brings clarity, peace of mind, and a foundation for moving forward with confidence and care. Getting answers might take time, but you deserve to feel informed, empowered, and supported every step of the way.

What Is Multiple Sclerosis?

Multiple Sclerosis (MS) is an autoimmune disease that affects the central nervous system, disrupting communication between the brain and the body. Symptoms often come and go, which can make it difficult to recognize a pattern. No single test can confirm MS—but a combination of methods helps doctors make a reliable diagnosis.

Here’s a closer look at how Multiple Sclerosis is diagnosed:

Medical History & Neurological Exam

Your doctor will ask about current symptoms, medical background, and perform a physical and neurological exam to evaluate balance, reflexes, coordination, strength, and vision. These early steps help determine whether MS is a possible cause of your symptoms.

MRI Imaging

An MRI (Magnetic Resonance Imaging) is one of the most important tools in MS diagnosis. It can detect lesions (areas of inflammation or damage) on the brain and spinal cord—hallmarks of Multiple Sclerosis.

Lumbar Puncture (Spinal Tap)

This test collects cerebrospinal fluid to look for specific antibodies that indicate immune system activity in the central nervous system. Abnormal results support an MS diagnosis.

Evoked Potential Tests

These tests measure the electrical activity in the brain in response to sensory stimuli. Delays in response can suggest nerve damage consistent with MS.

Blood Tests

While blood tests can’t confirm MS, they’re used to eliminate other conditions that cause similar symptoms, such as infections, vitamin deficiencies, or autoimmune diseases like lupus.

The process can feel long and, at times, frustrating. MS is a “rule-out” diagnosis, meaning doctors often eliminate other conditions first. But persistence pays off—and with the right medical support, answers are possible.

How multiple sclerosis is diagnosed - Cadense

Jun 23, 2025

What Happens After a Diagnosis?

After receiving a diagnosis, one of the first things many people ask is: Now what? The truth is, managing MS goes beyond medications and appointments—it’s about making thoughtful choices that support your day-to-day life.

Many people with MS experience issues with walking, foot pain, or loss of balance due to muscle weakness, nerve damage, or fatigue. The right footwear can make a huge difference in confidence, comfort, and stability. That’s where Cadense comes in.

At Cadense, we design shoes for people living with conditions like Multiple Sclerosis—because we believe that comfort, ease, and support should never be out of reach. Our shoes for MS are built with:

  • Wide openings and adjustable closures for easy on-and-off, even on challenging days
  • Anti-slip soles to help reduce the risk of falls
  • Lightweight cushioning to reduce fatigue and support each step
  • Stylish, everyday designs so you never have to compromise on how you feel or look

When you live with MS, your shoes become more than an accessory—they’re part of your care plan.

Supportive Footwear Can Help

If you or someone you care about is in the process of understanding how Multiple Sclerosis is diagnosed, we see you. This path may feel uncertain, but with the right tools, information, and support, you can move forward with strength and confidence.

And when it comes to moving—literally—we’re here to help. Explore our collection of shoes for Multiple Sclerosis to find comfort you can count on, one step at a time.

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Posted by: Johannes Sauer

Johannes is the CEO and Co-Founder of Cadense and passionate about helping people with walking difficulties. He was immediately drawn to the mission of the company because his cousin lost his lower leg in a tragic motorcycle accident a few years ago and is experiencing walking difficulties ever since. Johannes brings over a decade of experience in working for consumer product companies to Cadense. He holds an MBA from the University of Graz in Austria. Johannes lives with his family in Santa Barbara, CA.

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